Veins and blood vessels are an important link in the chain of our health. In the literal sense, veins, vessels and capillaries are the most important highways along which the energy of life flows. Any disturbances in these structures: varicose veins, blockage, stretching and a number of other problems can significantly reduce the quality of life and, in some cases, lead to serious consequences and the development of serious diseases. Therefore, it is important to monitor your health constantly and always.
In the article we will consider the drug “Detralex” as a means of treating and preventing diseases of the veins and blood vessels. Let's talk about what makes it special, what its composition is, how to take it correctly and when a positive effect is achieved.
Pharmacodynamics, pharmacokinetics
The medicine has a venotonic, angioprotective effect. After its use, venostasis, capillary permeability, and vein distensibility decrease.
In addition, taking the medicine helps:
- Improving microcirculation
- Lymphatic drainage
- Increased tone of venous walls
- Reducing the interaction of leukocytes and endothelium
Basically, active substances are excreted through the intestines, a small part of them through the kidneys.
Effect of the drug on varicose veins
Detralex is classified as a phlebotropic drug. This effective remedy has a complex effect on the body. The active components that make up the medicine act as follows:
- They increase vascular tone, reduce the degree of wall permeability, prevent stagnation of venous blood, increase blood circulation, and help reduce blood pressure.
- Strengthen vascular walls, speed up the movement of blood through the veins.
In combination with auxiliary components, the active substances have the following effects:
- suppress the production of enzymes that contribute to the development of the inflammatory process;
- neutralize the effect of free radicals, which lead to damage to vascular walls;
- avoid the penetration of leukocytes into nearby tissues;
- reduce the content of leukocytes in tissues susceptible to inflammation;
- help reduce the amount of toxic substances in the body;
- improve the process of blood microcirculation.
Although the drug has an antioxidant effect and other beneficial properties, it cannot be used during breastfeeding, for the treatment of children under 18 years of age, or for those with allergies to the active components.
In what cases are Detralex tablets prescribed?
The use of Detralex is advisable for venolymphatic insufficiency of the legs, in which the following occurs:
- pain and swelling
- heaviness in the legs
- convulsive manifestations
- trophic disorders
The pharmaceutical agent is prescribed for the treatment of acute hemorrhoidal attack.
Important to know: Detralex for hemorrhoids and varicose veins is used as a symptomatic drug, most often used as a complex treatment.
When is it prescribed?
The active substance of the drug is diosmin, the second active substance is hesperidin.
Detralex is intended to combat varicose veins. This disease is accompanied by disturbances in blood flow, which lead to the formation of blood clots, nodes and the development of swelling. Therapy in the early stages of the disease is vital. Otherwise, serious and life-threatening complications develop. Therefore, to prevent these problems, it is recommended to use the drug at the first symptoms of the disease. At the initial stages of pathology development, treatment will be more effective.
Experts say that treatment with Detralex is necessary in the following situations:
- if your legs constantly hurt;
- cramps bother you at night;
- legs feel heavy, especially at the end of the day;
- trophic ulcers appeared on the skin;
- worried about hemorrhoidal attacks;
- a vascular network is visible under the skin and nodes are palpable.
This is a tablet medicine. Its dosage is determined depending on the stage of development of the disease and the presence of complications. Each patient requires an individual approach.
Detralex, how much to drink
It is wise to take Detralex only as prescribed by a doctor; self-medication can lead to undesirable consequences. Based on the complexity of the situation and the course of the disease, the doctor must determine the duration of the therapeutic course. It is useful to know that even taking several tablets can lead to drug addiction.
If necessary, the doctor may prescribe a second course of medication.
For chronic hemorrhoids, tablets are usually taken for 2-3 months.
Contraindications and adverse reactions
The medicine has practically no contraindications. You should avoid taking it if you are allergic to any of the ingredients.
Negative effects from taking appear in extremely rare cases. They usually present with nausea and stomach upset. Sometimes dizziness, headache, and deterioration in general health may occur. An allergy may appear in the form of a skin rash.
To date, there have been no cases of drug overdose. In the chronic stage of the disease, experts usually advise taking the medicine in courses of 2-3 months. In case of acute form, take in weekly courses.
If after this time the symptoms have not disappeared, the patient should schedule an examination with a specialist.
Instructions for use
For varicose veins, the doctor may prescribe 2 tablets per day. The medicine should be taken one at a time, during lunch and dinner.
In the acute stage of hemorrhoids, doctors prescribe 6 tons of tablets per day in the first 4 days of treatment, and in the next 3 days you need to drink 4 tablets every day. The daily dosage must be divided into several doses; the medication should be taken during meals. After taking the medicine for a week, the dose is reduced by 2 times, taken only once a day.
Composition of Detralex
The main active ingredients of Detralex are diosmin 900 mg (90%) and hesperidin 100 mg (10%). As well as excipients to ensure better absorption of active substances and their transportation to their destination, that is, to the vascular system. Both active ingredients of Detralex are flavonoids, which are obtained from orange peel. Detralex is a semi-synthetic drug with proven effectiveness and numerous clinical studies.
An important component in the production of Detralex is the process of micronization (grinding) of the active substance. This is an expensive stage of production. Few enterprises include it in the drug manufacturing cycle. But it is this procedure that minimizes the effect of the drug on the gastrointestinal tract and promotes good bioavailability, that is, absorption in the body. Thus, the good tolerability of Detralex is one of its main advantages over other phlebotonics.
Release form and dosage of Detralex
Detralex tablets
The tablet form of the drug Detralek is available in dosages of 500 mg and 1000 mg.
The number of tablets in packages is 30 and 60 pcs. For the treatment and prevention of varicose veins for 1 month and 3 months, respectively (1 tablet 1 time per day). The drug is also available in a package of 18 tablets at a dosage of 1000 mg - for the treatment of hemorrhoids. Detralex suspension
Detralex suspension is ready for use, easy to swallow, does not require dilution or washing down with water - you just need to squeeze the suspension from the bag directly into your mouth/spoon and swallow. This form is perfect for people leading an active lifestyle, for those who are often on the road and flying. 1 sachet contains 1000 mg of active ingredient. There are 30 sachets in one package.
Detragel
Detralex gel (Detragel) for topical use in complex therapy for the treatment and prevention of varicose veins. As an independent remedy, it can be used for fatigue and heaviness in the legs, as well as pain, swelling, contusions and bruises. Does not leave marks on clothes and skin. In the production of the gel, an innovative substance delivery system is used, due to which the active substances quickly penetrate the body. Can be used either alone or in combination with the venotonic Detralex in the form of tablets or suspension. Available in volumes of 40 mg and 80 mg.
Indications for Detralex
The drug Detralex is indicated for eliminating and alleviating the symptoms of venous diseases of varying severity. A course of Detralex eliminates the symptoms of venous-lymphatic insufficiency:
- pain and discomfort in the limbs;
- cramps in the legs and feet;
- feeling of heaviness and fullness;
- "tired" legs.
It also effectively fights the visible manifestations of venous-lymphatic insufficiency:
- swelling;
- trophic changes in the skin and subcutaneous tissue;
- venous trophic ulcers.
- spider veins
Treatment of varicose veins
Regimen for taking Detralex for varicose veins
In order to prevent swelling and heaviness, varicose veins and venous insufficiency, if there is a risk (sedentary/standing work, increased stress), the recommended dose is 1 tablet per day for 3-6 months. After a break, the course of the drug can be repeated. Monotherapy using only detragel is also suitable as a preventive measure.
Treatment of hemorrhoids
Hemorrhoids are the result of impaired blood circulation and an inflammatory process in the choroid plexus of the rectum, which is accompanied by thrombosis, varicose veins, as well as sclerosis of the veins with frequent complications in the form of bleeding and pain during defecation. Detralex for hemorrhoids is prescribed in a short course, lasting 7 days.
Dosage regimen for hemorrhoids
Contraindications
The drug Detralex has one main contraindication - individual intolerance to the active substances and components of the drug. In rare cases, during clinical studies, side effects such as nausea, vomiting and stool upset, allergic reactions in the form of urticaria and itching were observed (therefore, persons with a tendency to allergies of various origins should take the drug with caution), headaches and weakness.
Before you start taking Detralex orally, you should notify your doctor about all the existing characteristics of your body in order to draw up the most successful treatment regimen with Detralex.
Can Detralex be used by pregnant women?
In the first trimester of pregnancy, the medicine can be prescribed only in exceptional cases when the risk of blood clots is high.
In other situations, according to the doctor’s decision, the drug is prescribed after the 20th week of pregnancy.
Detralex is also prescribed to pregnant women for hemorrhoids and varicose veins; it helps cope well with swelling of the legs.
Obstetricians and gynecologists are of the opinion that the drug does not have a negative effect on the body of the woman and the fetus. Therefore, if necessary, they consider it advisable to use it.
Detrolex reduces the risk of developing thrombophlebitis or exacerbation of hemorrhoids in pregnant women.
Medicine Detralex
Detralex is produced by the French company Servier, whose production complex is located, among other things, in Russia.
The main principle of the company producing Detralex is environmental friendliness, naturalness and safety. Therefore, all Servier products are a guarantee of high quality. Detralex is no exception. THIS IS INTERESTING: one of the components of Detralex - hesperidin - is extracted from the peel of unripe oranges. Moreover, the choice of unripe fruits is approached with special care - their size should not exceed 2.5 cm in diameter. Because the smaller the fruit, the more valuable substances it contains. The main countries for orange production are Mexico, Egypt, China and Morocco. First, the orange peels are dried and crushed. This is how the basis for Detralex is obtained - a complex of flavonoids or a flavonoid fraction, which is then sent for refinement and production of the drug we are familiar with.
Interaction
No special studies have been conducted to identify the interaction of Detralex with other drugs. However, to date there are no reports of negative interactions between the drugs and other medications.
Special studies regarding drug and other forms of drug interaction have not been conducted. However, given the extensive experience of post-registration use of Detralex, to date there are no statements about its adverse interaction with other drugs.
