Andipal: instructions for use - at what pressure can it be taken?

Many people take Andipal tablets for blood pressure, not understanding how this effect is expressed, but appreciating its quick and mild hypotensive effect. The drug contains analgesic and antispasmodic components, due to which blood vessels and smooth muscles relax, and the hypotensive effect is secondary. However, doctors successfully use Andipal, prescribing it for the initial stages of hypertension and other concomitant diseases. How the product works, what its composition is, indications and methods of use will be discussed further.

At what pressure is the drug used?

Andipal can only be taken with high blood pressure. The drug does not treat hypotension and does not eliminate the causes of the pathology. The main effect of consuming the drug is a decrease in the intensity of symptoms accompanying high blood pressure. For this reason, Andipal is considered as an emergency drug.

The maximum level at which taking the medication is justified is 160 mmHg. At higher levels, it is not recommended to consume Andipal. This is due to the effect of bendazole in the tablets. The substance first increases blood pressure and then lowers it.

Analogues and substitutes

Level 4 ATC code matches:
Analdim

Reopirin

Tempalgin

Spazgan

Benalgin

Pentalgin ICN

Pentalgin N

Pentalgin

Analgin

Renalgan

Tetralgin

Spasmalin

Maxigan

Sedal-M

Piralgin

Baralgin M

Sedalgin Plus

Baralgetas

Revalgin

The drug has no analogues in terms of its main active ingredient.

Analogs for antispasmodic effect:

• Nomigren
• Papazol-UBF
• Papazole
• Urolesan
• No-Shpalgin
• Unispaz
• Teodibaverin

Pharmadynamics and pharmacokinetics

Andipal begins to act 15 minutes after administration. This is due to the fact that the active components of the drug are quickly absorbed into the blood. The condition of a person with high blood pressure is normalized by improving cerebral circulation and stopping the release of adrenaline.

Analgin, entering the body, helps reduce the pain symptoms of migraines. The substance also reduces the severity of swelling in soft tissues, which provokes an increase in body temperature.

Papaverine eliminates spasms of smooth muscles in the digestive organs and in the walls of blood vessels. By dilating the arteries, blood flow improves.

Dibazol reduces heart rate and normalizes breathing. Phenobarbital in the drug has a sedative effect on the cells of the central nervous system.

Pharmacodynamics and pharmacokinetics

This is a combined drug that has a vasodilator, analgesic and analgesic effect. A good antispasmodic, which determines the use of Andipal for blood pressure.

Metamizole sodium, which is part of the composition, reduces body temperature and relieves pain. Once in the gastrointestinal tract, the substance is well and quickly absorbed and blocks the prostaglandin system of arachidonic acid, increasing the sensitivity threshold of pain centers in the hypothalamus .

Papaverine hydrochloride dilates blood vessels (reduces the level of calcium in cells) located on the periphery and significantly reduces the overall tone of the smooth muscles of the surface of internal organs.

Bendazole is an antispasmodic, dilates blood vessels, stimulates the spinal cord, and restores nerve endings in the periphery.

Phenobarbital exhibits its sedative properties and enhances the effects of other components of the drug.

Composition and release form

Andipal is available in the form of round tablets of white or yellowish color. There are distinctive marks on the surface of the tablets. At the pharmacy, the drug is sold in cardboard or paper packages containing 10 tablets of the drug.

1 pill contains the following active ingredients:

• analgin – 0.25g;
• dibazol – 0.02 g;
• papaverine – 0.02 g;
• Phenobarbital – 0.02 g.

Among the auxiliary components of the medication are:

• potato starch – 47.7 mg;
• talc – 9.25 mg;
• stearic acid – 2.9 mg.

Price for Andipal

Andipal tablets in Russia will cost about 40 rubles per pack of 20 pieces.

In Kyiv pharmacies the price of tablets will be about 20 UAH. for 10 pcs.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

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Pharmacy24

• Andipal forte No. 100 tablets PAT Monfarm, Ukraine
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PaniPharmacy

• Andipal tablets Andipal B tablet. No. 10 Ukraine, Monfarm JSC

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Indications for use

The tablets are sold in pharmacies without a doctor's prescription. Indications for taking the medicine:

• hyperthermia accompanied by an inflammatory process;
• increased blood pressure;
• vegetative-vascular dystonia;
• spasms of smooth muscles of the gastrointestinal tract;
• circulatory disorders in the brain.

The medicine is prescribed to reduce pain in the postoperative period, during complex diagnostic procedures and with high blood pressure.

Who is the drug indicated for?

The annotation clearly states what Andipal tablets are for and describes their use. Most often, neurologists and therapists prescribe this medicine against headaches of various origins, including migraines. The use of this drug is especially justified for vascular headaches, the causes of which are associated with cerebral vascular dysfunction.

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The medicine will be useful for colic and other types of pain from the peritoneal organs; it quickly relieves spasm of smooth muscles when:

• increased gas formation;
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Andipal tablets help with high blood pressure. As they normalize blood pressure levels, they are taken only in the initial stages of hypertension. Advanced arterial hypertension requires treatment with more powerful and long-acting drugs.

As a one-time measure, the drug can be taken when the “upper” pressure increases to 160-170 units, but not higher.

The tablets quickly reduce any pain, while they have a sedative effect. Hypertensive patients with a tendency to crisis states cannot relieve headaches with Andipal - they may experience sudden surges in pressure after its effect ends.

Contraindications

In addition to hypotension, Andipal has other contraindications for use:

• blood pathologies – coagulation disorders, anemia;
• all types of glaucoma;
• arrhythmia;
• sensitivity to the components of the drug;
• kidney and liver diseases;
• hereditary disorder of pigment metabolism;
• obstruction of the gastrointestinal tract.

The medicine must not be taken during pregnancy, regardless of trimester. Clinical trials have revealed the harmful effects of the drug's components on the developing fetus. Taking Andipal during gestation threatens to cause deviations in the psychological state of the child - developmental delays, impaired speech functions.

The drug helps with headaches, so patients believe that it can be used to combat hangover. The instructions say that the drug should not be used with alcoholic beverages, since the active substances of Andipal greatly enhance the effect of alcohol on the human body. This can lead to unpredictable consequences.

Safe interval

Compatibility between Andipal and alcohol is impossible. The patient must be sober. The drug can be taken no earlier than 12-15 hours after the person drank alcohol. This rule only applies if the dose of alcohol was insignificant.

You should be careful about your health. Taking medications is almost always incompatible with alcohol. And andipal is no exception. In order for the treatment to give positive results, you need to carefully read the instructions for the drug and strictly follow the doctor’s instructions.

Admission rules

In order to get the maximum effect from the drug, you must adhere to some rules during treatment:

1. Take the drug once when signs of hypotension appear. Take 1-2 tablets at a time.
2. Use the drug for long-term therapy only with the permission of a cardiologist. The duration of therapy does not exceed 10 days
3. Take the drug with food. A tablet taken before meals causes irritation of the mucous membranes of the stomach and intestines.
4. For long-term use, do not take more than 4 tablets per day.

The dosage of the medication may vary depending on the therapeutic goals:

• to relieve headaches, Andipal is taken in 2 doses with an interval of 1 hour;
• for hypertension, drink the drug 2 times a day for 3 days.

In the initial stages of hypertension, Andipal is taken only in extreme cases. Failure to comply with the dosages prescribed by the doctor may lead to the appearance of a collaptoid state.

For blood pressure, the drug is indicated for children from 8 years of age. For hypertension, they are allowed to take 2-3 tablets per day.

Compatibility of andipal with alcohol

Before using the medicine, you should carefully read the instructions. Andipal absolutely not be taken after alcohol. The drug is also contraindicated in case of hangover.

The recommendations in the instructions cannot be ignored. Alcohol in combination with this drug causes quite serious harm to health. Even a small glass of low-alcohol beer or wine when interacting with the drug leads to severe intoxication.

Andipal is not taken to relieve hangover pain. The body contains a high content of ethanol breakdown products. If you add drug components to them, you get a very dangerous mixture. As a result, toxic and stressful manifestations of the body develop. The negative consequences of combining Andipal with alcohol can even lead to death .

They appear:

• severe nausea and vomiting;
• shortness of breath and lung collapse (compression of one or both lungs, pneumothorax);
• extensive hemorrhages of internal organs;
• dizziness and loss of consciousness;
• exacerbation of stomach and duodenal ulcers;
• coma, even death;
• stroke;
• general deterioration of health associated with severe poisoning;
• some mental reactions (the patient has impaired clarity of thinking, it is difficult for him to navigate in space, he behaves inappropriately).

During treatment with Andipal, it is strictly forbidden to drink alcohol. Tablets can only be taken in a completely sober state.

The medication itself is hepatotoxic. It puts a lot of stress on the liver. In combination with alcohol, this provokes severe pathologies, such diseases as liver failure and cirrhosis are possible. The kidneys are also severely affected.

If the patient has taken Andipal while intoxicated, vomiting must be promptly induced . An adsorbent will help block the effects of toxins. Next you need to call an ambulance.

Adverse reactions

Therapy with Andipal can cause:

• allergic skin rashes;
• feelings of drowsiness;
• liver dysfunction.

After taking Andipal, it is not recommended to drive a vehicle or perform work that requires increased concentration.

Among the side effects of the drug are:

• blood thinning;
• development of a depressive state;
• depression of the nervous system;
• decreased motor activity.

Due to numerous adverse reactions, Andipal is not recommended for use as a pain reliever. For this purpose, drugs with a milder therapeutic effect are selected.

In case of an overdose of the drug, the following is observed:

• drowsiness;
• dizziness;
• collptoid state.

Interaction with other medications

When Andipal is combined with other synthetic drugs, an increased hypotensive effect may be observed. Such means include:

• nitrates – Nitrosorbit, Monosan, Dinisorb;
• myotropic antispasmodics – Drotaverine, Nosh-pa, Papaverine;
• diuretics – Veroshpiron, Furosemide, Uregit;
• beta blockers - Nebivolol, Penbutolol, Anaprilin.
• Ganglioblockers – Gigroniy, Pentamin.

If Andipal is used in conjunction with other non-narcotic drugs, the toxic effect on the body may be increased. It is not recommended to take the drug with sorbents, as they reduce the level of absorption of the active components into the gastrointestinal tract. The shelf life of the drug is 2.5 years.

Patient reviews

Alexander 34 years old . “The drug is well suited for slightly elevated blood pressure, but for people whose blood pressure rises to 200 mm Hg. he won't help. The product saves me from headaches and nausea that occurs after overwork or drinking coffee. I recommend that people who are taking medicine for the first time consult a doctor. The undeniable advantage of the medicine is its cost.”

Stanislav is 54 years old . “I took Andipal in the initial stages of the development of hypertension, when the pressure rose to 140-160 mm Hg. Art. Over time, the drug stopped helping, since the tablets only slightly lower blood pressure and are addictive if used frequently. I believe that the medicine is suitable for young people who do not suffer from chronic hypertension. For people with gastrointestinal diseases, it is better to give preference to other medications, since Andipal negatively affects the mucous membranes of the intestines and stomach.”

Elena is 41 years old . “My parents have been drinking Andipal since 2010. Recently, the drug has stopped helping due to the fact that addiction to its components has occurred. During treatment, parents noted a side effect – nausea.”

Svetlana, 36 years old . “I had to take Andipal while on vacation. After drinking whiskey I had a severe headache. I drank the drug at risk to my health, since the medicine is not compatible with alcohol. Fortunately, there were no adverse reactions. I advise anyone who is planning to undergo a course of medication to consult a doctor first. This medicine has many side effects."

Tatyana, 38 years old . To take the drug as an antipyretic or analgesic, it is necessary to control the blood pressure level. The product is not suitable for people suffering from low blood pressure. These tablets help me with hypertension associated with changing weather or stress. Among the main advantages I can note the low cost. The only drawback of the product is the lack of instructions for use.

Doctor's recommendations online

When taking Andipal for blood pressure, a rapid therapeutic effect is observed. Its effectiveness is evidenced by reviews from patients suffering from hypertension. Before using the product, you must ensure that there are no contraindications. If you take the medicine for hypotension or to relieve a hangover, you can get negative consequences in the form of nausea, weakness and an allergic reaction. The medication is suitable for one-time or short-term use. For course treatment, Andipal is taken only with the consent of the doctor, since it affects the composition of the blood and is addictive.