Zelenin drops: indications, instructions for use, where to buy at an affordable price

Zelenin drops are a natural preparation based on extracts of belladonna, lily of the valley and valerian. It has a complex effect - antispasmodic, sedative, analgesic. It is sold in pharmacies at an affordable price, and you can buy the medicine only with a prescription.

pharmachologic effect

The product is a combination preparation of plant origin. Its effect on the body is determined by the components that make up the drug.

Belladonna leaf provides an antispasmodic and m-anticholinergic effect. This component prevents the stimulating effect of acetylcholine and also reduces the level of pancreatic secretion; gastric, salivary, lacrimal, bronchial, sweat glands. The action of this component ensures a decrease in the tone of the muscles of the bile ducts, gallbladder, and gastrointestinal tract. Belladonna leaf causes tachycardia and improves AV conduction. Also, when taking this ingredient, there is dilation of the pupils, an increase in intraocular pressure , a decrease in the outflow of intraocular fluid, and paralysis of accommodation occurs as a result of its influence.

Lily of the valley tincture provides a cardiotonic effect on the body, increases the frequency and intensity of contraction of the heart muscle.

Valerian rhizome with roots acts on the body as an antispasmodic and sedative. Valerian helps normalize sleep. Facilitates the onset of natural sleep. The sedative effect after taking valerian appears slowly, but is stable. A choleretic effect and activation of the secretion of the gastric and intestinal mucosa are also noted. Valerian slows down the heart rate and dilates coronary vessels. It indirectly affects the functioning of the myocardium through neuroregulatory mechanisms, also through a direct effect on the automatism and conduction system of the heart.

Menthol is a local irritant. It has an analgesic, venotonic, reflex, antianginal, and coronary dilation effect.

Bradycardia

Bradycardia is a type of cardiac arrhythmia characterized by a slowing of the heart rate to 55 beats per minute or lower. It is the norm for athletes who systematically experience significant physical activity. In this case, we talk about physiological (functional) bradycardia. However, more often it is pathological in nature and serves as a symptom of heart disease. This condition is based on the inability of the sinus node to produce electrical impulses more than 60 times per minute, or to distribute them correctly along the conduction pathways.

Indications for use

Indications for the use of this drug are the following diseases:

• spasm of the gastrointestinal tract;
• vegetative-vascular dystonia ;
• symptoms of hepatic and renal colic ;
• chronic form of cholecystitis ;
• high excitability;
• hyperacid gastritis ;
• biliary dyskinesia.

The use of Zelenin drops is advisable for cardioneuroses, which are accompanied by bradycardia .

Nosological classification (ICD-10)

• G90.9 Autonomic nervous system disorder, unspecified
• K29.6.1* Hyperacid gastritis
• K31.3 Pylorospasm, not elsewhere classified
• K80.5 Bile duct stones without cholangitis or cholecystitis
• K81.1 Chronic cholecystitis
• K82.8.0* Dyskinesia of the gallbladder and biliary tract
• N23 Renal colic, unspecified
• R10.4 Other and unspecified abdominal pain
• R45.1 Restlessness and agitation

Contraindications

When starting treatment with Zelenin drops, contraindications must be taken into account. The following contraindications are noted:

• high sensitivity to the product;
• angle-closure glaucoma ;
• prostate hypertrophy, in which there is a violation of the outflow of urine;
• severe form of atherosclerosis of the heart vessels;
• cardiosclerosis;
• endocarditis , myocarditis .

Diagnostics

The main symptom of the pathology in question is a rare pulse. With sinus bradycardia, heart contractions have a regular rhythm. The sonority of heart sounds remains unchanged. Some patients experience irregular breathing.

To clarify the diagnosis, the doctor prescribes additional tests:

• ECG;
• ultrasound sonography of the heart;
• bicycle ergometry with load;
• transesophageal electrophysiological study of cardiac conduction tracts.

The latter method allows you to differentiate the functional and organic forms of heart rhythm disturbances.

Instructions for use (Method and dosage)

The instructions for Zelenin drops stipulate that adult patients take 20–25 drops twice or thrice a day. The drops should be diluted in a small amount of water.

If Zelenin drops are prescribed to children, the instructions for use stipulate that for a child over 12 years of age the drops are dosed at the following rate: one drop per one year of the child’s life. The duration of therapy depends on the tolerability of the drug, as well as on the effectiveness of its effect in each specific case.

Types of bradycardia and causes of its occurrence

According to its localization, pathological bradycardia of the heart can be:

• sinus. Appears due to a malfunction of the sinus node;
• caused by heart block. In this case, the sinus-atrial or atrioventricular conduction of impulses is disrupted.

Sinus bradycardia, depending on the causes that provoked it, is divided into the following forms:

1. Organic. Appears as a result of any cardiac pathology: dystrophy or myocardial infarction, cardiosclerosis, myocarditis.
2. Neurogenic (not associated with heart disease). This form can be caused by many factors: increased intracranial pressure, brain tumors and brain hemorrhages, various neuroses, vegetative-vascular dystonia, head bruises, wearing an excessively tightly tied tie or tight collar. Bradycardia is typical for patients with reduced thyroid function. Its cause may be a stomach or duodenal ulcer.
3. Medicinal. This form is caused by taking certain medications, in particular, cardiac glycosides, morphine, β-blockers, calcium channel blockers, etc.
4. Toxic. Develops with severe intoxication due to sepsis, typhoid fever, uremia, hepatitis. Toxic bradycardia is caused by poisoning with phosphorus compounds.

Sometimes the cause of the slow heart rate cannot be determined. This form is called idiopathic.

Cardiac bradycardia in a child or adolescent is usually caused by the same causes as in an adult. Such children require systematic monitoring by a cardiologist.

Women sometimes develop sinus bradycardia during pregnancy. This is a temporary condition that is not considered a pathology and goes away on its own after childbirth.

special instructions

During therapy, you should drive carefully, as well as engage in other potentially dangerous activities that require maximum concentration.

Elderly patients, as well as adolescents over 12 years of age, are treated with the drug with caution, since the drug contains alkaloids of the atropine group.

To increase the activity of the drug, drops are sometimes prescribed simultaneously with hawthorn preparations .

Before starting treatment with drops, you should definitely consult with a specialist, since the doctor must clearly instruct the patient about the need for such treatment and the specifics of taking the drug.

Overdose and drug interactions

In case of overdose, the following phenomena may occur:

• dry mouth;
• problems with eye accommodation;
• dizziness;
• dilated pupils;
• tachycardia (attacks).

In such situations, taking the drug should be stopped immediately. Symptomatic treatment is indicated, or, as a last resort, going to an ambulance.

The drug can be used simultaneously with other medications, but it is important to take into account the interaction features:

• Zelenin drops enhance the hypnotic effect;
• they also enhance the effects of central nervous system depressants;
• in combination with drugs against arrhythmia, their effect is reduced;
• Zelenin's potassium enhances the therapeutic effect of antispasmodics and drugs that are used to treat bradycardia.

Price of Zelenin drops, where to buy

The price of Zelenin drops ranges from 70 to 85 rubles per 25 ml bottle.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

Pharmacy Dialogue

• Zelenin drops (bottle 25ml) YAF
  93 RUR order
• Zelenin drops (25ml bottle) Tverskaya FF

  90 rub. order

• Zelenin drops (25ml bottle) MFF

  83 RUR order

show more

Treatment of bradycardia

Physiological and mild types of pathology that do not cause much discomfort to the patient do not require therapy. If the decrease in heart rate is caused by medications, then dose adjustments or drug replacement are carried out. All other forms are eliminated with medication. The basis of treatment should be to eliminate the problem that caused the slow heart rate.

Symptoms associated with cerebral hypoxia are relieved by products containing belladonna (Bellaspon, Bellataminal, Besalol, Zelenin Drops), Eleutherococcus extract, ginseng root, and caffeine.

Drugs that can increase heart rate include:

• "Atropine sulfate";
• "Izadrin";
• "Normosecretol";
• "Orciprenaline sulfate";
• "Ephedrine hydrochloride."

Injection solutions and tablets for bradycardia are selected by the doctor, taking into account the clinical picture, contraindications, the patient’s age and concomitant diseases.

Zelenin drops

Many pharmaceutical industry products are based on natural plant extracts that have one effect or another. Thus, the soothing properties of valerian, belladonna and lily of the valley have been used in the manufacture of Zelenin drops. A cocktail of tinctures of these herbs, created by the director of the Institute of Therapy, V.F. Zelenin. prescribed to women for neuroses associated mainly with stress, premenstrual syndrome and fatigue.

Composition of Zelenin drops

The drug includes natural ingredients. Let's consider their properties in more detail.

Belladonna (belladonna) tincture

This plant is known to be poisonous due to its chemical composition. In the Middle Ages, it was used to induce hallucinations, and more severe poisoning was accompanied by convulsions, a sharp drop in blood pressure, and an increase in temperature that could cause death from respiratory paralysis. But nevertheless, minimal doses of belladonna have a therapeutic effect and are used for kidney stones and bronchial asthma. The ability to enhance the contractility of the internal sphincters while simultaneously reducing the tone of the gastrointestinal tract is used in the treatment of gastritis and inflammatory diseases of the mucous membranes of the stomach.

Valerian tincture

Valerian officinalis is famous for its calming and natural sedative effect, which is imparted by the essential oils and alkaloids it contains. Valerian is widely used as an independent drug to calm the nervous and cardiac systems, and as an integral component in preparations.

May lily of the valley

This plant is most often used in the perfume industry. Just like belladonna, it is a poisonous plant and, if consumed internally, can cause convallatoxin poisoning. Poisoning is accompanied by an increase in blood pressure with disturbances in heart rhythm (arrhythmia) up to cardiac arrest. In medicinal doses it is used for tachycardia and acute or chronic heart failure, because has cardiotonic properties.

Menthol

Widely used in pharmaceutical, food and cosmetic industries. It has a cooling effect, aromatizes, and has a slight local anesthetic effect.

Indications for the use of Zelenin drops

Zelenin drops are prescribed and taken in the presence of diseases and symptoms such as:

• increased nervous excitability;
• impaired motility and inflammatory processes of the biliary tract;
• VSD;
• spasmodic manifestations of the gastrointestinal tract;
• renal colic;
• inflammatory diseases of the gastric mucosa (gastritis);
• decreased appetite.

Zelenin drops are also prescribed for bradycardia. At the beginning of treatment, Zelenin drops are prescribed in a minimum dose - 5 drops in the first three days. Then, if well tolerated, the dose is increased.

Contraindications for the use of Zelenin drops

Due to the ability to increase the heart rate, Zelenin drops are not recommended for tachycardia. Also, direct contraindications for Zelenin drops are:

• diseases of the cardiovascular system (endocarditis, cardiosclerosis);
• peptic ulcer of the duodenal intestine and stomach;
• glaucoma;
• individual allergic reaction of the body.

Taking this drug reduces your concentration, which can negatively affect driving and other activities that require close attention.

Taking Zelenin drops

This drug is taken on an empty stomach (20-30 minutes before meals) in a dosage of 20-30 drops in half a glass of water. To achieve a therapeutic effect, it is recommended to take the drug 2-3 times a day.

Zelenin drops: what are they for and how to take them?

Today we will tell you about what Zelenin drops are, what they are intended for, how to use them, etc. In addition, you will be presented with reviews from consumers who have once used or are currently using this drug.

General information

Zelenin drops are a combined herbal medicine with cardiotonic, antispasmodic and sedative effects. This remedy was developed by a clinician, Soviet therapist, Doctor of Medical Sciences, Honored Scientist of the RSFSR (in 1946) and academician of the USSR Academy of Medical Sciences (in 1944) Vladimir Fillipovich Zelenin.

Composition of the drug

Zelenin drops are a herbal medicine that includes tinctures of lily of the valley, belladonna leaves, valerian and menthol.

Appearance and release form

The presented medicine is available in dropper bottles made of dark glass, 25, 20, 30, 40 or 15 ml. One cardboard box contains detailed instructions for use, as well as a jar with a clear and slightly brownish liquid with a pronounced tincture aroma.

Properties of the drug

The complex of herbal remedies that are included in the presented drops has an antispasmodic and calming effect, and also provides moderate stimulation of the heart muscle.

pharmachologic effect

The antispasmodic and calming effects of Zelenin drops are determined by the presence of plant components in it. To understand why this product is popular among consumers, let’s look at the principle of its operation in more detail. To do this, we will tell you about the properties of the herbal tinctures included in the medication:

• Lily of the valley tincture. This drug has a cardiotonic effect.
• Belladonna leaves. This tincture significantly reduces the secretion of the sweat, gastric, bronchial, salivary and lacrimal glands, as well as the pancreas. In addition, the mentioned plant has m-anticholinergic and antispasmodic effects.
• Menthol. The presented component acts as a local irritant. In addition, it has analgesic, coronary dilation, venotonic, antianginal and reflex effects.
• Valerian root tincture. This remedy has an antispasmodic and sedative effect, and also accelerates the onset of natural rapid sleep. It should be especially noted that the sedative effect of this component is stable, although it occurs rather slowly. Among other things, valerian root significantly slows down the heart rate, dilates coronary vessels, has a choleretic effect and increases the secretion of the mucous membrane of the gastrointestinal tract.

Indications for use of the drug

According to the attached instructions, Zelenin drops should be used in the presence of the following pathological conditions:

• hypo- and anacid gastritis;
• irritability;
• hepatic colic;
• vegetative-vascular dystonia;
• spasms of the gastrointestinal tract;
• renal colic;
• biliary dyskinesia;
• hyperacid gastritis;
• chronic cholecystitis;
• as part of combination therapy – chronic heart failure;
• increased excitability;
• decreased appetite.

Contraindications to the use of the drug

The drug Zelenin (drops) is not recommended for use with the following deviations:

• intolerance to the main components of the drug;
• prostatic hypertrophy, which occurs with disturbances in the outflow of urine;
• angle-closure glaucoma;
• gastritis (hyperacid);
• myocarditis;
• peptic ulcer (including mucosal erosion) of the duodenum and stomach;
• endocarditis;
• under the age of 13.

Instructions for use of the drug

Zelenin drops should be taken orally half an hour before meals several times a day (2 or 3 doses per day). According to the attached instructions, the amount of the drug for adults and adolescents should not exceed 20-30 drops (in a single dosage). In this case, it is advisable to take the medicine with half a glass of water.

Side effects

The drug itself never causes side effects. But in case of overdose, patients may experience allergic reactions. Experts associate this manifestation with the presence of belladonna tincture in the pharmaceutical product. Thus, with incorrect doses, a person may experience increased heart rate, dry mouth, and dizziness. As a rule, all of these side effects disappear immediately after stopping the use of the drug. It should also be noted that long-term use of Zelenin drops often leads to depression of the central nervous system. This manifests itself in the form of drowsiness, lethargy, apathy, loss of appetite, slow heart rate and nausea. In such cases, it is better to stop using the medication and use another remedy with a similar effect.

Attention!

Those who regularly use the presented drug should know that:

• With the systematic use of Zelenin drops in patients diagnosed with bronchial asthma with the simultaneous use of drugs “Izadrin”, “Salbutamol”, “Berotek”, etc. special care should be taken. This is because this combination of medications can cause a very rapid heart rate.
• During the period of therapy, special care must be taken when driving vehicles, as well as engaging in other dangerous activities that require good vision, speed of psychomotor reactions and increased concentration.
• Some consumers confuse Zelenin drops with the medicine Corvalol. In this regard, it should be remembered that the first drug is used for bradycardia, and the second - in the presence of tachycardia.

Interaction with other tools

When taking Zelenin drops simultaneously with sleeping pills that depress the central nervous system, the effects of these drugs are significantly enhanced.

Shelf life and storage conditions

Zelenin drops must be stored out of the reach of small children and in a slightly cool place (at a temperature of no more than 25 ° C). The shelf life of this drug is exactly two years from the date of manufacture.

Zelenin drops: consumer reviews

Reviews about this product are very varied. Some consumers claim that this is a good sleeping pill that effectively protects against nightmares and panic attacks. This drug is easy to use (you only need to drink 20 drops), it completely contains no “chemicals”. Zelenin drops are much more effective than other herbal products. Moreover, such a medicine is especially attractive for those who are not willing to pay a large amount for a pharmaceutical drug. Other consumers note that the belladonna leaves included in this product have a side effect in the form of severe dilation of the pupils. In this regard, the eyes of some patients become sensitive to bright light, and also quickly get tired after working at the computer. It is also worth noting that after taking Zelenin drops, many consumers immediately begin to feel sleepy. That is why it is recommended to take them only in the evening.

Complications

Moderate or mild cardiac bradycardia may not cause hemodynamic disturbances. However, a significant decrease in heart rate (up to 40 beats or less) leads to insufficient blood flow to vital organs and their oxygen starvation. As a result, serious damage to the brain, kidneys, liver, intestines, lungs and disruption of their normal functioning can occur.

The brain suffers the most from impaired contractile function of the heart muscle (myocardium) and insufficient blood supply. Its hypoxia causes convulsions or episodes of loss of consciousness lasting up to a minute. This is the most serious complication, since breathing may stop during an attack. In case of frequent loss of consciousness with a sharp drop in blood pressure, the issue of implanting a pacemaker is decided - a device that artificially generates electrical impulses with the required frequency.