The drug ascorutin - use and contraindications

What substances are included in the drug?

The list of components in the medicine opens with vitamin C, which has a beneficial effect on the functioning of the immune system. Ascorbic acid is responsible for human performance and optimization of biochemical processes. The second active element is vitamin P. They are also called phaonoids. The drug ascorutin is recommended, among other things, to improve the functioning of the vascular system. With regular dosage intake, high blood pressure ceases to bother you, and the capacity of the capillaries increases. Another advantage of vitamin P is that it saturates the body with useful antioxidants.

Six causes of pelvic varicose veins in women

Varicose veins in our body can be localized not only on the legs. The pelvic area is another place where varicose veins can also occur. A pathological condition in which there are dilated veins in the pelvis, as a rule, occurs in women and is accompanied by discomfort and periodic aching pain in the lower abdomen. In men, varicose veins of the small pelvis also occur, but they manifest themselves mainly as dilation of the veins of the spermatic cord (varicocele). This pathological process in men can be accompanied by discomfort, heaviness in the scrotum, and pain during intimacy.

According to statistics, varicose veins of the small pelvis, or as it is also called, chronic pelvic pain syndrome, occurs mainly in young women - from 18 to 48 years old. The number of patients with this disease increases several times with age. The statistics are disappointing. Thus, at the age of 18−19 years, varicose veins of the pelvic veins are detected in 15−18% of women, and by the age of 48 their number increases to 70−80%.

Causes of pelvic varicose veins:

The first reason is physical inactivity. This also includes the specifics of the patient’s work, “sedentary” or “standing” work. Due to a person's long stay in orthostasis, venous outflow is disrupted and this leads to stagnation in the pelvis. The valves in pathologically dilated veins no longer fit tightly to each other, a gap is formed between the valves and the blood drains down due to the force of gravity. In such veins, the blood thickens, and this can subsequently lead to thrombosis.

The second reason is pregnancy. During pregnancy, the uterus increases in size and begins to press on the underlying veins. Also, during pregnancy, hormonal levels change, and the volume of circulating blood in the pelvis increases.

But to reassure women preparing for conception and pregnancy, such varicose veins do not pose a direct danger. With pelvic varicose veins, childbirth is usually uneventful. An unpleasant point - 30-40% of pregnant women experience dilation of the veins of the vulva and perineum. But we must remember that immediately after childbirth, these veins decrease significantly, and after a year they completely disappear. After childbirth, pelvic varicose veins remain in only 2−6% of patients.

The third reason is the presence of various types of gynecological pathologies that are treated with hormonal drugs.

The fourth reason is smoking. Smoking is very dangerous while taking hormonal contraceptives. Smoking causes blood to thicken, as do hormonal contraceptives. Hence the many ridiculous accidents known in medicine, when smoking girls who took hormonal contraceptives died from thrombosis.

The fifth reason is obesity. With excess body weight, the load on blood vessels increases significantly.

The sixth reason is the environmental situation in the region of residence; air pollution in cities, especially in megacities, increases the risk of developing varicose veins.

The main symptoms of varicose veins of the small pelvis:

1. painful periods.
2. periodically occurring pain in the lower abdomen, as well as in the pelvic area, radiating to the sacrum, lower back, and perineum.
3. Pain and discomfort in the vulva or vagina, during and after intimacy;
4. profuse mucous discharge from the vagina, usually in the second half of the menstrual cycle.
5. visible expansion of venous vessels in the genital area, in the groin. “Stars”, “nets” on the buttocks and back of the thighs.

WHAT TO DO IF YOU DETECT SYMPTOMS OF PELVIC VARICOSE VARICOSIS?

If you find all of the above in yourself, then do not delay visiting a doctor, otherwise possible complications will not take long to appear.

The first doctor you should see is a gynecologist.

He will conduct an examination and prescribe all the necessary examinations. All patients with suspected pelvic varicose veins undergo an ultrasound examination of the abdominal organs.

To clarify the diagnosis, the patient is referred to a phlebologist. They perform duplex ultrasound scanning of the veins of the lower extremities (USDG), which allows them to obtain a complete picture of the venous outflow.

In difficult cases, a phlebologist may prescribe additional examination methods (CT, MRI or diagnostic laparoscopy). To establish an accurate diagnosis and determine the extent of the disease, these studies are often sufficient.

Degrees of varicose veins of the small pelvis:

1st degree - pelvic veins up to 5 mm in diameter (damage to any venous plexus of the pelvis is noted), the course of the vessel already takes on a tortuous appearance;

2nd degree - vein size from 6 to 10 mm; varicose veins on ultrasound are visible throughout the entire pelvis, and can only affect the ovarian plexuses, or veins in the uterus, or myometrial veins;

Grade 3 is total varicose veins of the small pelvis, varicose veins have a diameter of more than 10 - 12 mm.

HOW TO TREAT PELVIC VARICOSE VEINS?

Non-drug treatment methods:

• Fighting physical inactivity. If work involves prolonged sitting or standing - after 1 - 1.5 hours
• Quitting smoking, alcohol (especially if you are pregnant!);
• wearing compression garments (stockings, tights) to improve venous outflow from the lower extremities;
• wearing comfortable shoes, avoiding high heels.
• Diet (exclusion from the diet of salty, spicy, fried foods). Salty foods always retain fluid in the body, which leads to edema and increased blood pressure - thereby worsening the outflow of blood through the veins. It is necessary to include more fiber (fruits, vegetables, greens) in your diet.
• Contrast shower (especially in the hips, perineum, lower abdomen).
• Therapeutic exercise and breathing exercises.

Drug treatment:

1. Phlebotonics (Phlebodia or Detralex) - to improve the tone of varicose veins, reduce their permeability;
2. Horse chestnut extract (escusan) - to relieve inflammation and swelling;
3. Troxerutin (troxevasin) - to improve the outflow of blood from varicose veins, increase the tone of the veins, reduce inflammation and swelling;
4. Vitamin C (ascorutin) - to strengthen the walls of blood vessels, reducing their fragility.

PS: Venous gels and ointments are not used in the treatment of pelvic varicose veins due to the internal location of the affected veins.

Doctors recommend a mandatory combination of drug therapy with wearing compression stockings (stockings, tights). During pregnancy there is a special need for compression garments. Also, during pregnancy, of the phlebotonics, only Phlebodia can be used and only in the second trimester; other drugs are not recommended.

Surgery:

Surgery is a last resort measure, which is used when drug correction is impossible and ineffective, and the disease is very advanced and can cause a number of complications.

Depending on the prevalence, location and diameter of pathological veins, various techniques are used. In cases where surgical intervention is necessary, the selection of the type of surgical procedure is individual, since everything depends on the location and extent.

What contraindications exist

A preliminary conversation with a doctor is the only way to avoid complications. He will immediately say that the drug should not be taken by those who have an increased level of blood clotting. Even after taking a small dose, the risk of blood clots increases many times over. A strict prohibition applies in cases where the patient is diagnosed with the following conditions:

• stones in the kidneys;
• diabetes mellitus or a hereditary predisposition to it;
• elevated calcium levels;
• allergy to certain components or hypersensitivity to them;
• low potassium levels.

Antiplatelet agents and anticoagulants: what is the difference?

First of all, it must be emphasized that blood thickness and excessive blood clotting are different processes. And it’s precisely the latter that medications are designed to combat, which prevent the severe consequences of excessive coagulation, thrombus formation, and also prevent this very coagulation and thrombus formation, the therapist notes.

To solve this problem, there are two large groups of drugs: antiplatelet agents and anticoagulants. Here it is worth saying right away that for those people who are interested in drugs for “blood thinning”, for example, for the purpose of prophylactic use, only drugs from the first group, that is, antiplatelet agents, are suitable. A typical representative of this group is acetylsalicylic acid in low doses.

“I would especially like to highlight that it is extremely dangerous to use such a remedy for viral infections. Especially without consulting a specialist. Only a doctor can make a decision about discontinuing or replacing if you are taking medications based on such acid,” says Tatyana Romanenko. For example, in children with a viral disease, taking acetylsalicylic acid can lead to Reye's syndrome, which manifests itself as severe damage to the liver and brain.

But why are anticoagulants needed? “This group of drugs prevents the formation of blood clots, stops the growth of existing blood clots, and also enhances fibrinolysis, that is, they dissolve an already existing blood clot. Disaggregants cannot do this. Classic representatives of anticoagulants include heparin and warfarin. No one will take warfarin on their own, since it is prescribed to patients, for example, with artificial heart valves for therapeutic purposes,” says Tatyana Romanenko.

You are responsible for yourself. When self-medication is useful and safe Read more

Antiplatelet agents, the doctor notes, can be bought without a prescription as a preventive measure. To understand how certain drugs work and why they are prescribed, you need to know the physiology of the process of hematopoiesis and its flow through the vessels. The purpose of antiplatelet agents is to prevent platelet aggregation.

“The main job of platelets is to participate in stopping bleeding; they form the primary, white thrombus. They are also involved in the formation of the final, red, or fibrin thrombus. Platelets constantly circulate through vessels of any caliber - from the aorta to capillaries, and monitor the presence of damage to the vascular network. As long as there is no damage, platelets are not activated. As soon as a vessel injury occurs, platelets begin to show activity - they stick to the damaged wall and aggregate, or stick together. This is how a platelet plug, or primary white thrombus, is formed. Also, activated platelets begin to produce biologically active substances, a whole cascade of reactions occurs, more and more platelets are involved in the process, the vessel wall contracts, the blood coagulates, and the bleeding stops,” explains Romanenko.

But here, too, there may be conditions when aggregation does not disrupt the integrity of the vessel walls. The same white blood clots appear, but atherosclerotic vascular damage does not increase. When even a small piece is torn off, platelets can be “deceived” and begin to become active near the atherosclerotic thrombus or the site of its detachment. Accordingly, antiplatelet agents should prevent platelets from sticking to each other, as well as their adhesion to blood vessels.

The general indications for prescribing antiplatelet agents are prevention. “They are prescribed as a means of preventing postoperative thrombosis, for various thrombophlebitis due to varicose veins, for chronic cerebral ischemia and atherosclerosis. But, of course, their main task is to prevent vascular accidents, that is, heart attack, stroke due to coronary heart disease and atherosclerotic lesions of the carotid arteries,” says Tatyana Romanenko.

Question answer

Will we face a shortage of imported medicines?

Strict adherence to dosage

Before starting the course, the doctor will give the necessary recommendations. The patient is strictly prohibited from engaging in independent activities, both in terms of increasing the dose and increasing the duration of use. Also possible negative consequences of such actions:

• failure of the kidneys;
• increased blood pressure levels;
• allergic attack;
• disruption of the pancreas.

The listed disorders may be irreversible, so you should carefully monitor the body’s reaction. From the moment the patient started taking it, the patient began to suffer from headaches, excitability, insomnia, rash, vomiting - all this indicates the need to immediately stop taking it. The doctor will conduct an examination and give the necessary recommendations.

Read more useful articles, as well as news from around the world, on the Nur.kz portal.