The drug Trental, which improves blood circulation, is produced in the form of tablets and a concentrated solution for infusion. The cost of the medicine depends on the form of the medicine and packaging. You can buy Trental at a price of 100-300 rubles per package.
The active substance in pentoxifylline is a xanatine derivative. The component is contained in the following quantities:
- 100 mg, 400 mg in soluble film-coated tablets.
- 20 mg in one ml solution for infusion.
In order to exclude possible allergic reactions when taking the product, it is necessary to pay attention to the auxiliary components that were used to create the drug. Trental instructions also contain all recommendations for use and focus on contraindications.
Causes
The main cause of atherosclerosis of the vessels of the lower extremities is a violation of lipid metabolism - an increase in the level of cholesterol in the blood, and especially its “dangerous” fraction of low-density lipoproteins (LDL). However, an increase in high-density lipoproteins (HDL) does not cause atherosclerosis.
Elevated cholesterol levels alone are not enough to cause the disease. There must also be risk factors that affect the vulnerability of the artery wall, its protective properties, etc. These include:
- Smoking is the most dangerous risk factor and needs to be discussed separately. Even smoking several cigarettes a day leads to damage to the vascular endothelium; with high cholesterol, this gives a high risk of cholesterol deposition at the site of the lesion and the beginning of plaque formation. When smoking a large number of cigarettes per day, this risk increases significantly.
- Hypertonic disease
- Overweight
- Diabetes
- Alcohol abuse
Strengthening the blood vessels of the legs with folk remedies
You can supplement the basic methods of strengthening the vascular system by resorting to traditional medicine. Folk remedies will help improve the condition of the circulatory system, eliminate the feeling of heaviness and even swelling of the lower extremities. For these purposes, healing decoctions and infusions, foot baths, etc. are used.
There are many recipes for healing herbal foot baths. This is how baths are used based on the following herbal infusions: dandelion, red clover, chamomile, nettle leaves, St. John's wort, linden blossom, etc. The selected herbs are poured with boiling water in advance and allowed to brew for 15 minutes, after which the resulting decoction is added to warm water. The water procedure for the feet lasts 15-20 minutes.
!
Garlic, honey and lemon are incredibly popular in alternative medicine recipes.
They are used to cleanse vascular walls from cholesterol plaques, increase the elasticity of the vascular wall and reduce the permeability of small capillaries. All these products are rich in biologically valuable substances. Therefore, there are various combinations and treatments with these products. Wrapping legs with garlic is widespread; nowadays it is extremely rarely used due to the low effectiveness of the method. To do this, you need to chop a couple of large heads of garlic with a garlic press, mix them with a small amount of butter (butter) and stir until a homogeneous paste is obtained. When applying the mass to the legs, special attention should be paid to painful areas of the veins. Then wrap your feet in cellophane and wrap them with a bandage.
Taking various herbal infusions is also considered an effective method of strengthening blood vessels. An infusion of yarrow or a decoction of hop cones infused in a water bath is useful.
In conclusion, I would like to add that regardless of how you decide to strengthen the vascular system, it is important to lead a healthy lifestyle and, first of all, give up bad habits and be physically active. Love yourself and your body will love you back!
Symptoms, diagnosis
The main and earliest symptom of obliterating atherosclerosis of the arteries of the lower extremities is intermittent claudication. When walking a certain distance, the patient begins to feel fatigue, heaviness in one or both legs, and then pain, forcing him to stop and continue moving after a short rest.
The stage of the disease is even determined by the length of the pain-free walking distance. From 500 m to 1 km – stage 1, from 200 to 500 m – stage 2A, less than 200 m – stage 2B, less than 50 m and pain at rest – stage 3. Stage 4 of atherosclerosis of the extremities is gangrene.
When examining the patient, attention is drawn to a decrease in the calf muscles, dystrophy of the nail plates, and a decrease in the amount of hair on the legs. A characteristic symptom is the absence of pulse in the feet, popliteal, and femoral arteries (depending on the level of the lesion).
Important methods for diagnosing atherosclerosis of the vessels of the lower extremities are ultrasound (ultrasound ultrasound, doppler ultrasound, duplex angioscanning), angiography.
Contraindications
An absolute contraindication is intolerance to the active substance and other components in the medication. The drug is not prescribed for people under the age of 18, as well as during pregnancy and lactation. Other contraindications for Trental 100, the instructions for use focus on:
- Severe bleeding of any etiology.
- Hemorrhages in the brain and retina.
- Myocardial infarction.
With extreme caution and only after assessing the patient’s condition, the drug is prescribed for the following pathologies:
- Cardiac arrhythmia.
- Low blood pressure.
- Chronic heart failure.
- Stomach and duodenal ulcers.
- Kidney failure.
- Liver pathologies.
Do not use the medicine after surgery, or if you are prone to bleeding.
Treatment of atherosclerosis of the vessels of the lower extremities
Lifestyle changes, non-drug treatment
Patients with atherosclerosis of the arteries of the extremities, as a rule, need to change their lifestyle.
First of all, you need a COMPLETE cessation of smoking. Reducing the number of cigarettes smoked, of course, has a positive effect on the course of the disease, but the risk of damage to the vascular wall still remains.
Overweight patients need to lose weight.
An important factor in reducing blood cholesterol levels (especially its dangerous fractions - LDL) is following a diet low in animal fats.
Patients suffering from hypertension and diabetes mellitus need to be monitored by an appropriate specialist (therapist, endocrinologist) to correct these diseases.
Against the background of drug correction, training for the development of collateral circulation is desirable. The fact is that with obliterating atherosclerosis, the main vessels are affected. In this case, blood circulation begins to occur through small bypass (collateral) vessels. With good development of collateral circulation, limb ischemia can be minimized even with complete closure of the lumen of the main artery. Along with medications that help improve collateral circulation (they will be discussed below), training walking is used using special techniques on a treadmill and just on foot.
Recommendations for training walking: patients are recommended to walk 2-3 hours a day, not at a fast pace, so that there is no pain in the legs. At the same time they exercise on a treadmill. They start by selecting a walking speed along the path that does not cause fatigue in the legs for at least 10 minutes of continuous walking. Then increase the speed by 0.5 km/h. They begin walking at this speed, when fatigue and pain in the lower leg appear, they rest until the discomfort completely disappears, then they resume walking again until discomfort appears. The average walking time on the path is 30-40 minutes per day. The goal is to increase the distance of pain-free walking to 1.5 km, after which the walking speed is increased by another 0.5 km/h, etc. Training should be done under the supervision of a doctor.
Dosage
The dose and method of administration are determined by the doctor after examining the patient. In this case, the severity of the circulatory disorder against the background of a specific disease and the person’s condition must be taken into account. Treatment must be carried out under strict control of blood pressure.
According to the instructions attached to the drug, oral administration is permitted in accordance with the following recommendations:
- Treatment intake: 3 tablets (100 mg) three times a day.
- Possible increase in dosage to 6 (100 mg) tablets three times a day.
- The maximum single dose is no more than 2 (100 mg) tablets.
Tablets are usually indicated for maintenance therapy. They are taken after meals. They must be swallowed with plenty of clean water. If there are pathologies of the kidneys and liver, then the dosage is reduced by 2 times. There are also other recommendations in the instructions that need to be studied.
The infusion solution is prepared from 100 - 600 mg of medication. It is diluted in 0.9% sodium chloride solution (250 - 500 ml). Droppers are placed 1-2 times a day. It is imperative to test for compatibility when using other infusion solutions.
Drug treatment
There are many medications that are used for obliterating atherosclerosis of the lower extremities.
They can be divided into several groups:
- Antiplatelet agents - thrombo ACC, cardiomagnyl, trental, plavix, reopoliglucin.
- Drugs that reduce blood viscosity - vesel due f (sulodexide), phlogenzyme, wobenzym.
- Agents that improve peripheral blood circulation and microcirculation - alprostan (vasoprostan), nicotinic acid, xanthinol nicotinate.
- Agents that promote the development of collateral circulation - Actovegin, solcoseryl.
- Drugs that lower blood cholesterol levels - Torvacard, Crestor, etc.
- Other medicines – chimes, analgesics (for pain), antibiotics (for purulent-necrotic ulcers), etc.
Typically, patients are permanently prescribed one of the acetylsalicylic acid drugs for life - thrombo-ass or cardiomagnyl. Other drugs are prescribed in courses, depending on the stage of the disease and clinical manifestations.
It is believed that twice a year patients require hospitalization in the vascular surgery department for courses of conservative therapy - intravenous infusions, hyperbaric oxygen therapy, physical therapy.
Effects of the drug and indications
The drug trental, the instructions for use indicate, reduces blood viscosity and improves its fluidity. The active substance has a slight myotropic vasodilator effect. Such combinations of properties help, after taking the drug, to improve microcirculation in areas where circulatory disorders are observed. The active substance in the medicine is quickly absorbed into the gastrointestinal tract, which guarantees a quick effect. When smoking, the therapeutic effect of the drug is significantly reduced.
Trental tablets are indicated for use in cases of impaired peripheral circulation due to the development of atherosclerosis. Its effectiveness has been proven in a pathology known as “intermittent” claudication. This insidious pathology can immobilize a person at any time. Its main symptom is acute pain in the legs, caused by deterioration of blood circulation in the arteries and their narrowing.
Trental 100 is also prescribed, the instructions confirm this, for trophic disorders. The medicine alleviates the condition of patients with trophic ulcers, which often occur against the background of varicose veins and thrombophlebitis. The drug is indicated in the complex treatment of gangrene and frostbite.
It is recommended to use trental for cerebrovascular accidents. This pathology can be provoked by cerebral atherosclerosis. Symptoms of the disease are the following:
- Inability to concentrate.
- The occurrence of periodic dizziness.
- Problems remembering simple information.
Ischemic and post-stroke conditions are also indications for the drug. When using the drug, it is possible to improve the condition of patients against the background of rapid restoration of blood flow. Indications are degenerative changes in pathologies of the vessels of the inner ear, which lead to hearing loss.
Surgery
Surgical treatment is possible in the presence of narrowings (stenoses) of large vessels, mainly in the popliteal-femoral segment or above. Reconstructive operations for damage to the arteries of the leg are practically not used.
For small stenoses, stenting is possible - installing a stent in the area of stenosis in a minimally invasive way (through a puncture in the femoral artery), which restores the patency of the artery.
In case of significant narrowings, reconstructive operations on blood vessels are used - bypass surgery, prosthetics.
With timely and correct treatment of obliterating atherosclerosis of the vessels of the lower extremities, it is most often possible to stabilize the process and avoid late complications - trophic ulcers, gangrene.
Adverse reactions
When the medicine is used correctly, adverse reactions of the body are rarely observed. As a rule, negative reactions occur when contraindications are violated, an overdose or non-compliance with the infusion rate.
The most common side effects occur from the nervous system. They may manifest as headaches. Negative reactions are also often associated with insomnia and internal anxiety.
Sometimes swelling and redness of the skin of the face may appear. In severe cases, an overdose develops tachycardia or arrhythmia, as well as other disruptions in the functioning of the cardiovascular system. Severe allergic reactions and signs of gastrointestinal bleeding may occur.
If dangerous symptoms appear and the general condition worsens, you should stop taking the drug. Treatment is symptomatic. If the patient’s condition cannot be stabilized, an ambulance should be called.
Diseases of the arteries of the legs, symptoms
The main complaint of peripheral arterial disease is pain in the legs when walking or during exercise. Due to narrowing of the arteries, the muscles receive less blood, which leads to pain or cramps. This is called intermittent claudication
. Once you stop and there is adequate blood flow to the muscles, the pain will gradually subside.
This may happen several times during your shopping trip, but this does not mean that you need surgery. If you are suffering from constant pain (rest pain), then the situation is more serious. This indicates that blood flow to the extremities is significantly reduced and you need urgent help to prevent serious complications from developing.
